Many of my patients are very suspicious of medical science, because they lump all "science" together, not realizing that most of the so-called science that they read about, and see on TV, is actually“Pseudo Science". As we move into the 21stcentury, the quality of medical science is taking a great step forward because more doctors are practicing "evidence-based" medicine. This is the practice of using treatments that have been proven effective by studies using the scientific method.
What is Pseudo Science? It is fraudulent claims based on "proof" that does not follow the standard scientific method. It could also be considered medical fraud. But how can the average lay person know which treatments have been judged effective by good science, and which are not? It can be very tricky!
Even the studies that are judged good enough to be published in reputable scientific or medical journals are often conflicting, because many are not adhering to the scientificmethod. Scientists are pressured to publish large numbers of papers, and limitations on time and funding can certainly affect their quality.
I simply reject most papers that I read in the standard medical journals, because they are obviously not a high enough quality to base a medical opinion upon. Sometimes this is due to poor study design, and sometimes because the number of patients is just too small to be significant statistically. In the second case, a study might be added to several others that support it, and could eventually be included in a review of many studies, and a valid conclusion could be drawn.
What is the Scientific Method?
It’s really quite simple! To see if a certain treatment works, for example, you perform a double-blind RCT. This stands for Randomized Clinical Trial which is double-blind (the patient doesn’t know whether he gets a placebo or the real medicine, and the scientist doesn’t know either, until the end of the experiment!). "Randomized" means that subjects are randomly assigned to be treated with either placebo or the real medicine. That way, you don’t get weird results because the two groups started out different to begin with.
The double-blind RCT then shows you how much of a difference the treatment made, as compared to placebo. The placebo (getting a treatment that seems the same as the real treatment, but is actually nothing) is very important, because of the placebo effect. This is the fact that most people get better to some extent just because they are getting some treatment, and they want to improve.
Even if an effect seems to be proved by a double-blind RCT, the results could be misleading due to chance. Maybe the treated patients were going to get better anyway. This is where the number of subjects becomes very important. The larger the number, the less likely the result is due to chance, and the more likely it is really the true effect of the treatment.
For the average person (who does not read medical journals) there are some basic rules that might help you to spot Pseudo Science! Dr Robert Park has written a short article on how to spot pseudo science, and I have copied it here:
The Seven Warning Signs of Bogus Science
By ROBERT L. PARK
The National Aeronautics and Space Administration is investing close to a million dollars in an obscure Russian scientist's antigravity machine, although it has failed every test and would violate the most fundamental laws of nature. The Patent and Trademark Office recently issued Patent 6,362,718 for a physically impossible motionless electromagnetic generator, which is supposed to snatch free energy from a vacuum. And major power companies have sunk tens of millions of dollars into a scheme to produce energy by putting hydrogen atoms into a state below their ground state, a feat equivalent to mounting an expedition to explore the region south of the South Pole.
There is, alas, no scientific claim so preposterous that a scientist cannot be found to vouch for it. And many such claims end up in a court of law after they have cost some gullible person or corporation a lot of money. How are juries to evaluate them?
Before 1993, court cases that hinged on the validity of scientific claims were usually decided simply by which expert witness the jury found more credible. Expert testimony often consisted of tortured theoretical speculation with little or no supporting evidence. Jurors were bamboozled by technical gibberish they could not hope to follow, delivered by experts whose credentials they could not evaluate.
In 1993, however, with the Supreme Court's landmark decision in Daubert v. Merrell Dow Pharmaceuticals, Inc. the situation began to change. The case involved Bendectin, the only morning-sickness medication ever approved by the Food and Drug Administration. It had been used by millions of women, and more than 30 published studies had found no evidence that it caused birth defects. Yet eight so-called experts were willing to testify, in exchange for a fee from the Daubert family, that Bendectin might indeed cause birth defects.
In ruling that such testimony was not credible because of lack of supporting evidence, the court instructed federal judges to serve as "gatekeepers," screening juries from testimony based on scientific nonsense. Recognizing that judges are not scientists, the court invited judges to experiment with ways to fulfill their gatekeeper responsibility.
Justice Stephen G. Breyer encouraged trial judges to appoint independent experts to help them. He noted that courts can turn to scientific organizations, like the National Academy of Sciences and the American Association for the Advancement of Science, to identify neutral experts who could preview questionable scientific testimony and advise a judge on whether a jury should be exposed to it. Judges are still concerned about meeting their responsibilities under the Daubert decision, and a group of them asked me how to recognize questionable scientific claims. What are the warning signs?
I have identified seven indicators that a scientific claim lies well outside the bounds of rational scientific discourse. Of course, they are only warning signs; even a claim with several of the signs could be legitimate.
1. The discoverer pitches the claim directly to the media.The integrity of science rests on the willingness of scientists to expose new ideas and findings to the scrutiny of other scientists. Thus, scientists expect their colleagues to reveal new findings to them initially. An attempt to bypass peer review by taking a new result directly to the media, and thence to the public, suggests that the work is unlikely to stand up to close examination by other scientists.
One notorious example is the claim made in 1989 by two chemists from the University of Utah, B. Stanley Pons and Martin Fleischmann, that they had discovered cold fusion; a way to produce nuclear fusion without expensive equipment. Scientists did not learn of the claim until they read reports of a news conference. Moreover, the announcement dealt largely with the economic potential of the discovery and was devoid of the sort of details that might have enabled other scientists to judge the strength of the claim or to repeat the experiment. (Ian Wilmut's announcement that he had successfully cloned a sheep was just as public as Pons and Fleischmann's claim, but in the case of cloning, abundant scientific details allowed scientists to judge the work's validity.)
Some scientific claims avoid even the scrutiny of reporters by appearing in paid commercial advertisements. A health-food company marketed a dietary supplement called Vitamin O in full-page newspaper ads. Vitamin O turned out to be ordinary saltwater.
2. The discoverer says that a powerful establishment is trying to suppress his or her work.The idea is that the establishment will presumably stop at nothing to suppress discoveries that might shift the balance of wealth and power in society. Often, the discoverer describes mainstream science as part of a larger conspiracy that includes industry and government. Claims that the oil companies are frustrating the invention of an automobile that runs on water, for instance, are a sure sign that the idea of such a car is baloney. In the case of cold fusion, Pons and Fleischmann blamed their cold reception on physicists who were protecting their own research in hot fusion.
3. The scientific effect involved is always at the very limit of detection.Alas, there is never a clear photograph of a flying saucer, or the Loch Ness monster. All scientific measurements must contend with some level of background noise or statistical fluctuation. But if the signal-to-noise ratio cannot be improved, even in principle, the effect is probably not real and the work is not science.
Thousands of published papers in para-psychology, for example, claim to report verified instances of telepathy, psychokinesis, or precognition. But those effects show up only in tortured analyses of statistics. The researchers can find no way to boost the signal, which suggests that it isn't really there.
4. Evidence for a discovery is anecdotal.If modern science has learned anything in the past century, it is to distrust anecdotal evidence. Because anecdotes have a very strong emotional impact, they serve to keep superstitious beliefs alive in an age of science. The most important discovery of modern medicine is not vaccines or antibiotics, it is the randomized double-blind test, by means of which we know what works and what doesn't. Contrary to the saying, "data" is not the plural of "anecdote."
5. The discoverer says a belief is credible because it has endured for centuries.There is a persistent myth that hundreds or even thousands of years ago, long before anyone knew that blood circulates throughout the body, or that germs cause disease, our ancestors possessed miraculous remedies that modern science cannot understand. Much of what is termed "alternative medicine" is part of that myth.
Ancient folk wisdom, rediscovered or repackaged, is unlikely to match the output of modern scientific laboratories.
6. The discoverer has worked in isolation.The image of a lone genius who struggles in secrecy in an attic laboratory and ends up making a revolutionary breakthrough is a staple of Hollywood's science-fiction films, but it is hard to find examples in real life. Scientific breakthroughs nowadays are almost always syntheses of the work of many scientists.
7. The discoverer must propose new laws of nature to explain an observation.A new law of nature, invoked to explain some extraordinary result, must not conflict with what is already known. If we must change existing laws of nature or propose new laws to account for an observation, it is almost certainly wrong.
I began this list of warning signs to help federal judges detect scientific nonsense. But as I finished the list, I realized that in our increasingly technological society, spotting voodoo science is a skill that every citizen should develop.
[NOTE: Robert L. Park is a professor of physics at the University of Maryland at College Park and the director of public information for the American Physical Society. He is the author of Voodoo Science: The Road From Foolishness to Fraud (Oxford University Press, 2002).]